Accelerating the pace of chemical risk assessment

Toward International
Progress

APCRA is an international governmental collaboration that brings together governmental entities engaged in development of new hazard, exposure, and risk assessment methods and approaches for their chemical evaluation activities.
To discuss progress and barriers in applying new tools to prioritization, screening, and quantitative risk assessment of differing levels of complexity. 
To discuss progress and barriers in applying new tools to prioritization, screening, and quantitative risk assessment of differing levels of complexity. 

Goals of
APCRA

Common understanding of current state of the science applications of New Approach Methods (NAMs), including the regulatory context.
Increased understanding of realistic benchmarks for performance of NAMs in different regulatory contexts.
Determine mechanisms to enhance data sharing capabilities.
Increase engagement and commitment to development and sharing of case studies of mutual interest.
Increased cross-Agency collaboration to strategically address barriers and limitations of use of NAMs in a regulatory context.

Publications

Yadvinder Bhuller
,
Deborah Ramsingh
,
Marc Beal
,
Sunil Kulkarni
,
Matthew Gagne
,
Tara S Barton-Maclaren
,

Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

Front. Toxicol., 04 November 2021 | https://doi.org/10.3389/ftox.2021.748406 Abstract: In 2012, the Council of Canadian Academies published the expert panel on integrated testing of pesticide’s report titled: Integrating emerging technologies into chemical safety assessment. This report was prepared for the Government of Canada in response to a request from the Minister of Health and on behalf…
Robert J.Kavlock
,

Publication after first APCRA Workshop in Washington DC

Title: Practitioner Insights: Bringing New Methods for Chemical Safety into the Regulatory Toolbox; It is Time to Get Serious BNA Daily Environment Report 223 DEN B-1, Pages 1-3

Background paper: Evolution of the Existing Substances Risk Assessment Program under the Canadian Environmental Protection Act, 1999

Official title: Chemicals Management Plan Science Committee background paper: Evolution of the Existing Substances Risk Assessment Program under the Canadian Environmental Protection Act, 1999 and considerations looking forward Chemicals Management Plan (CMP) Science Committee meeting: February 17 to 18, 2021
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Workshops

The fourth APCRA Workshop was hosted by US EPA (ORD) at Research Triangle Park, North Carolina, USA. Main Workshop Outcome:
The second APCRA heeting have been organised by the European Chemicals Agency in Helsinki in October 2017 Main Workshop Outcome:
As covid pandemic continued in 2021 also the sixth APCRA meeting was held online. Main Workshop Outcome:
Third APCRA workshop was organised by Health Canada in Ottawa. Main Workshop Outcome:
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